my friend, I just noticed that I have the same problem (virtualbox Win7 & FTDI cable) as you when trying to communicate with baud rates higher than 9600. I tested with 19200 and 38400, and indeed, as soon as I change this setting on the scope, the hardware communication stops, and I even need to disconnect the cable to restore communication. I saw in the programming manual, Table 1-2, that it is recommended to leave the default configuration (I'll send an image); however, I don't understand why the options to increase the baud rate exist if this is not possible. Could it be due to some limitation from not using a pure serial cable? Could someone show if this problem occurs with an RS232-RJ45 cable for a PC's serial port? In any case, I can communicate at 9600, so I'm not too concerned about the transfer speed at the moment. Finally, I've noticed that I'm unable to do data logging from the scope to the PC—can you? Could you show me how to do it? If you wish, you can contact me privately. Best regards!