In my tests all tested software versions (4.40, 5.40, 5.60, 5.70, 5.80, 5.90) worked with XP and the original mainboard (ADLINK M-815G).
But only 4.40, 5.40, 5.60 worked with any changed C2D mainboard (XP and Win7-x32). Versions 5.70, 5.80 and 5.90 did not work with any other mainboard than the original mainboard. Problem was that all drivers installed fine but simply the cards were not accepted (No valid ID in frame). My assumption is that some kind of hardware locking or compatibility check as added in the later versions.
I've not seen any real compatibility or stability issue in any mainboard (E8400, E6400, Q9400). No BSOD, nothing. Except that you might end up with "no valid ID in frame". And there might be limits when operating two different VGA cards in parallel where one runs the old XP driver.