I have a 2281S, which works well for me. The downside is that the fan noise is the worst of anything I own; the pitch grates the most. I try not to use it if I can. Plus, it cannot create battery models. Well, it can, but only discharging at a fixed 1A. So, for battery models, they recommend an SMU.
I was looking at the Keithley E36731A as a replacement, as it can both generate the models and emulate a battery. The biggest issue is that you buy the instrument but then have to rent or buy a license for BenchVue to use any of the battery emulation stuff. The annual rental is ~$900 a year; to purchase a permanent node-locked licence, add about 30% onto the unit's price. Oh, and they recommend you have the software on maintenance, that's a few hundred a year too.