Be careful of ground. Consider getting a differential probe for ungrounded and higher voltage work (such as power supplies).
BTW - One can utilize scopes, or a DMM, or any other device, for critical measurements (for example, you are measuring a single occurrence that will not happen again, or too costly to make happen again; or Need to refer to a physical property accurately like volt, ampere, ohm, Hz, SPL, lumens, etc. ; or Need great resolution for a very sensitive sensor).
Usually these types of measurements are run against external calibration. The simplest example (for a DMM) is if I work on mains I stuff the DMM in working mains. I don't trust a 0V shown until I am calibrated at 220v. It is even better to go back to the 220V and validate the DMM did not die between the two outlets... (It is critical because if the measurement is wrong I won't be around to do it again - becoming a 1 time measurement....)
Doing DC or ohms - compare against a fresh 9V battery (or better yet - a silver oxide battery) or a calibrator, measure a precision resistor salvaged from discarded T&M (in the same range as the DUT).
One can do the same with a scope. If one channel is down and both measure 4.8V instead of 5V - then the voltage isn't a clue. However, if one is 4.8v and the other reads 5v - it may be (per Fungus' post). The second (working) channel serves as a calibration reference against the first.
One can also work around limitations: If one is aware of the noise floor, one can raise the input signal for a good SNR using a calibrated amplifier. Use a mixer (properly) to work around bandwidth limitations, Etc. the options are endless...
Getting calibrated readings can get pretty complex pretty quickly - I did lots of these types of experiments in the Navy - it was all about calibrating the T&M chain. The hydrophone, the B&K charge amplifiers, the parametric and notch filters, the scopes, the recorders, the HP TRMS voltmeters, you had to plot and save a bathymetry (and work the predictions), plan the test with the operations team so that you know distances and depths fairly accurately, etc. In the ocean, everything needs to end up as dB re 1uPa @ 1yd in defensible accuracy.
Heck - eve a bad grounding scheme can destroy your test. So we'd calibrate the individual components and the setup as a whole for weeks prior to the live sea tests (and calibrate backup T&M in case something fell in the ocean - or decided to throw a tantrum) - Imagine the cost of redoing a test with a frigate or submarine because you could not figure out the SONAR equation...