I have a Wave Surfer 434, and when I first got it I had a similar sounding issue. On mine it would boot to Windows, start the X-Stream application, but then stop (I think there was a warning message, this was a while ago so I can't be more precise). It would however recognise the scope hardware and start the application properly when restarted (okay for hot boot, no go for cold boot).
In my case it was a bad electrolytic capacitor issue, mainly the ones on the PC motherboard. Mine was manufactured in mid-2004, so pretty well in the bad capacitors era, and quite a few of the motherboard capacitors were visually bad (domed, with dried discharge on the vents). I replaced every electrolytic capacitor in the scope (both motherboard and scope hardware), and that resolved the issue. The 434 has worked well since, and is still my main scope.
I'd consider doing something similar before digging much deeper, at least to the PC motherboard. Have fun, it's a classic Japanese design that's a mess on many PCBs and cables - pretty awful to work on.