An update. I've received the replacement 34465A last week and it was on continuously for about 100 hours so far. I've run a log over the weekend measuring the LTZ1000 and the meter drifted about 4ppm down, however ACAL this morning returned the results to within 1ppm of measured by HP3458A previously. The resistance ranges are now nice and stable, the attached graph shows 1 hour log for two 34465A and HP3458A - all for NPLC 100 measuring my 10K LTC450C reference resistor (taken at different times, obviously, but with a fairly constant temperature in the lab for each run). Keysight UK was very helpful in resolving this problem. I aslo should get the 3458A Opt 002 back from them later this week so I will have a freshly calibrated reference.
Cheers
Alex