I think the error on first turn on is due to a missing checksum because the EEPROM is still empty. Or something along those lines. I've used mine for over half a year now (went through five 9V batteries) and haven't seen it since.
I really don't get why people complain about input protection. It's not a multimeter that you hook up to random wires sticking out of a wall. It's an instrument for testing passive components.
From what I've read the Agilent would be a far worse choice: measurements jumping all over ther place, firmware bugs, defects, bad service. I haven't even heard of a defective DE 5000. Another little detail: the Agilent (wait, it's Keyhole now or something, right?) has printing on the rubber buttons that will eventually wear off, while the DE 5000 has the printing on the panel, under a clear plastic layer. Nice little detail IMHO.