None of these units worked when I got them. The newer custom chips seem to be fully encapsulated (black on the bottom) and have white sticky-on labels with the part numbers. The older custom chips are white on the bottom with exposed metal and have the part number printed (silk-screen?) directly on the chips. The E51 unit's VCO is white bottom so may have been replaced at some point.
And hopefully all of the custom ones (U401, U201, U300) have heatsinks on them!
Since you purchased these units broken, there's a possibility that there's more than one thing wrong. Sometimes people combine units to get one working unit and then sell off the broken units re-stuffed with broken parts as non-working. Just something to keep in mind.
For the "Low Amplitude & Offset" settings I am unable to get the offset correct. I can get the amplitude correct by adjusting A1R450 (square), R445 (sine), but the offset adjustment on R416 won't go high enough and I have about a -64mV offset error when the main output amplitude is set to 1V. I have tested pin 8 on U401 without the chip installed and it moves between +4.3V and -5.2V (my other E21 unit does the same). However with U401 installed it moves between +1.76V and -5.2V. On the E21 unit it goes between +2.3V and -5.2V. This difference is apparently not caused by the U401 chip itself because even if I swap between my two U401 chips the adjustment range is the same. On the other voltage ranges I was able to set the offset correctly.
Is the 64mV offset showing up on TP4 also? Perhaps there is a problem with the main output amp now?
If TP4 is not ok, are U401 pin 18 and 19 balanced?
What section of the adjustment procedure are you performing? A1R416 and A1R450 are mentioned in the Power Supply section, and then again in the Shaper Adjustments section. There are more detailed adjustments in the latter. If you haven't done so already, perhaps going through the shaper adjustments will tweak them and other pots to bring the offset into spec.
Not to be discouraging, but these things are a royal pain to adjust. The pots have way too much range and make the right setting sometimes hard to achieve, and there a several areas where there's a lot of interaction between adjustments. I think it took me a day.