I came across this project a while ago, I'm just getting around to digging into it since I need a new soldering setup anyway.
https://www.hackster.io/sfrwmaker/soldering-and-rework-station-for-t12-and-jbc-tips-ec2c44#overviewThe author mentions using an external transformer to isolate the power rails from ground as he's just using a non-isolated Meanwell 300w switching supply. I'm planning on using a Meanwell PID-250B which is a dual isolated power supply. That also gets rid of the onboard 5v DC-DC converter module by just adding a 5v connector from the PSU.
I started converting the main-board to KiCAD since there were a few things I didn't like, like the use of too many different styles of connectors, etc and I don't know EasyEDA very well. I wound up entirely re-doing the main PCB (haven't really looked at the others yet). As I was going through it I found the 5v converter section a little odd. He uses an MP1584 DC-DC converter module to get 5v from the 24v input which is fine, then uses a B0505S 5v isolated module before the 3.3v LDO. The input and output ground/commons are tied together on the B0505S as the op-amp section can't be isolated from the input the way it's done. I suppose the B0505S is cleaning up the 5v a bit but I'm not really sure that this has much use since it's common with the input that drives the irons etc...
I'm keeping the footprints for the MP1584 and B0505S on my PCB but not using them since I can bring 5v in from my PSU. I have a fairly lousy understanding of analog stuff, op-amps, etc, but I'm wondering if it would be worth the effort to isolate the 5v/3.3v grounds from the 24v ground. The OP amp section is the only thing that really makes it a problem to isolate both rails. Not sure what to do about it or if I should even bother. Any thoughts?