You still trying solve simple problem in a most complex way
You don't need regulated DC/DC for negative voltage. Maximum load current of this circuit is 2.5mA. Just use negative voltage (you say that you have -12V in system?) for power opamp and get required negative voltage from it's output. In this case you also don't need switch and discharge on this voltage rail.
Another point - gateing of 12V supply also wrong, you should use high side switch. You can try to find switch with current sense and get rid of separate current sense circuit.