I assume any nixie tubes you have are ancient, even if they have never been used. If they work well now I guess that eliminates any basic envelope softness issues, which tended to plague nixies. They are basically neon lamps, and their lifetimes are pretty much like neon lamps. Some work well for years. Others go dim, often very unevely, or start flickering erratically. I think the formed character types had more wear issues than the 7 segment and starburst ones, but that might just reflect the behaviour of the particular models I have used.