Back in the early 2000s I saw a SMPS designed to run from such a high voltage. It was complex, because one couldn't find many components with the required voltage ratings.
I don't think a flyback would be the best option, the reflected voltage and the leakage inductance spike could task even the highest rated Mosfets and diodes. Most likely a better solution will be a two-switch forward.
But I could be wrong, there may be newer devices and topologies to address specifically these scenarios.
Personally, since the power ratings are so low, I wouldn't immediately dismiss a custom 50/60 Hz transformer solution. I would at least investigate it.