Hello essele,
welcome in the 3458A club!
As the others already have said, it's no problem to replace these nvRAMs, especially the 2k CAL RAM, if you first save its data via GPIB, and then later transfer these cal constants to the fresh nvRAM.. I assume you have an appropriate programmer available.
Desoldering is very easy, as the pins are not sitting tight in their holes. If you use the same DALLAS chips, precision sockets are recommended, maybe also for the FRAM solution, if something goes wrong with the adapter.
It's a miracle, that these 30 year old data are not yet corrupted, or do you get error messages?
I see no problem to use OTPs instead of EPROMs, as FW 8 or 9 are the latest versions, even in the new Black Edition.
Your 2ppm/y option means, that the LTZ1000A already drifts that little, that a reduction of the oven temperature will not give any added value.
In contrary, you would initially have to do a re-calibration.
The modus operandi for the specified 8, 4 or 2ppm/year DCV drift is not described in the manual. So what is the 'proper use' ?
That oven temperature reduction makes most sense if the instrument is running 24/365.
If the instrument is turned on for a small period of time / year only, the drift should anyhow be very low, as a 'cold' LTZ1000 has nearly zero drift.
I wish you, that SN18A does not apply for your instrument, neither for the reference, nor for the U180.
Frank