Please take a look a Dr Franks nice summary in a related thread:
https://www.eevblog.com/forum/metrology/hp3458a-ocomp-delay-related-problems/msg1464930/#msg1464930 If you use a setting in which NPLC is greater than 10 NPLC, the 3458A just averages the samples of multiple 10 NPLC measurements. Also delay and OCOMP are used on every 10NPLC, so this leads to such a large measurement time. The APER-command integrates over the whole time instead of doing the mathematical 10NPLC/DELAY/OCOMP-averaging, therefore saving sample time.
Here are a few measurements i did which show the timing on a 3458A:
#OCOMP OFF, Delay default, NPLC 10,AZ OFF -> 0.2s
#OCOMP OFF, Delay default, NPLC 10,AZ ON -> 0.4s
#OCOMP OFF, Delay 1, NPLC 10,AZ ON -> 1.4s
#OCOMP OFF, Delay 2, NPLC 10,AZ ON -> 2.4s
#OCOMP ON, Delay default, NPLC 10, AZ OFF -> 0.4s
#OCOMP ON, Delay default, NPLC 10,AZ ON -> 0.8s
#OCOMP ON, Delay 1, NPLC 10,AZ ON -> 2.77s
#OCOMP ON, Delay 1, NPLC 10,AZ OFF -> 2.38s
#OCOMP ON, Delay 2, NPLC 10,AZ OFF -> 4.33s
#OCOMP OFF, Delay default, NPLC 100,AZ ON -> 4.05s
#OCOMP ON, Delay default, NPLC 100,AZ ON -> 8.25s
#OCOMP ON, Delay 1, NPLC 100,AZ ON -> 27.26s
#OCOMP ON, Delay 1, NPLC 50,AZ ON -> 13.65s
#OCOMP ON, Delay 1, APER 1,AZ ON -> 5.97s