My LTC6655 does not drift much when powered up, but does drift when powered down.
That implies that it suffers from hysteresis - there's no way to know if it's drifting while powered down, only power cycling it.
Let me put it this way - when I leave it running for several days (> 120h) it does not drift. Only when the temp is changing and this can be seen.
Even if I power cycle it, it does not drift. However, when it stays powered down for a week, the voltage value changes.
I really have to start logging it properly like Andreas, but what I can see right now I do not like it. I need to recalibrate the DUT every time the DUT (and vref) powered down for some time and this is just not right.