I have two HP419s, one working (part of an ESI 242 resistance measurement system) and one that's not. I've been struggling a bit to measure the working one's bias current. The method of simply measuring the difference between the zero mode and regular operating mode doesn't work for the HP419 due to its low input impedance of 100K. The meter moves around 100~200nv in the operating position which isn't that much different than when I have it shorted. Thus, the noise floor seems to be limiting this particular procedure. Also the lack of a shorting switch on the ESI doesn't help either as I'm always leery of my low thermal short. Ideas for measuring the current in light of the 100K input impedance would be greatly appreciated.
With regards to DMMs, their bias current and suitability for balancing high impedance sources, there are some DMMs that require one to adjust the bias current as part of the cal procedure. The Datron 1061,71,81 series comes to mind. Indeed, my Keithley 155 meter also has this adjustment. Mine was originally quite high (thanks mrdiode for pointing this out) and adjusting it brought it down to the femtoamp range. I'm guessing with careful adjustment, DMMs with adjustable current one could do the same.