I'd like a USB Isolated connector to my 240W AC Mains controller running an MCU connected to my Laptop USB.
First, verify your MCU has a High Speed (480 Mbit/s) USB 2.0 interface, and not a Full Speed (12 Mbit/s) one. For Full Speed, ADuM3160/4160 suffices, and in a self-powered configuration, requires only four bypass capacitors and four 24Ω±1% resistors (on each USB data line), although additional ESD protection would be useful, too. I've happily used these (in the form of ~ $10 eBay ADuM3160 isolators, after checking which DC-DC converter they use) with my own USB 2.0 Full Speed microcontrollers.
The difference between
ADuM3165 and ADuM3166 is clearly shown on the datasheet: whether the clock source or crystal is on the host side, or on the device side. Currently, ADuM3165 are in stock at Digikey and Mouser, but ADuM3166 are not. If you prefer the inductive ADuM iCoupler isolators over the capacitive TI ISOUSB211 one, then I personally would consider using a PCB layout that allows either ADuM3165 or ADuM3166 to be used, by simply duplicating the 24 MHz crystal and load capacitors on both sides, and only populating one depending on which chip is used. (The unused clock/crystal pins are grounds.) ADuM4165 and ADuM4166 are pin-compatible, but have a different (larger) footprint.
In addition to ADuM3165/3166/4165/4166, there is also the TI
ISOUSB211 isolator chip, which implements capacitive (as opposed to inductive/iCoupler) isolation, does not need a clock or crystal (the 24 MHz needed for retiming is internal), although thermal management is easier if you use external LDOs for 3.3V and 1.8V. Figure 10-2 in the datasheet corresponds to your use case. They also happen to be currently in stock at JLCPCB for PCB assembly, if you wanted to do a quick test board. (I'd like to do one myself, but I'm only a poor hobbyist on the electronics side, and simply happen to use isolators a lot. See
this thread for my experiences.)