This isn't really the right forum for this sort of question, and has nothing to do with Open Source Hardware I can see.
Contact your internet service provider (and email service provider if they are different) for assistance with your email configuration. ISP's regularly block port 25 from leaving their network, but they should be allowing port 587, and any email server operating as a smart (relay) host should be accepting authenticated connections to port 587 (SMTP submission)