I wouldn't discuss it with people I know, as it would be my decision, but I also wouldn't immediately go if offered.
I'd need to understand the risks presented to me, what would be expected of me physically and mentally, and how easy it would be to return to my life back on Earth.
I'd be quite more willing to work on the ISS, as it's a bit closer to home, and is not as risky of a proposition in my mind. Space travel with current technology is unpredictable, even to people who spend their entire lives trying to predict it, but it also taxes the people who go up there, who are honestly more like line techs, doing work for people on the ground more than anything else.
I would definitely go to space, or even settle for a zero G flight, because the ability to simply fly around would be absolutely incredible in my mind. I'm sure you get over it, and the minor issue of effectively having a head cold the entire time you're up there would probably get annoying, not to mention all the work that's expected of career astronauts.
If I live to see the moon or mars colonized with pedestrian travel to and from, I'd definitely take the trip.