The short story is that your ancient ISE 10 isn't supported on Windows 10.
And the rest of your complaint is nothing new, to be honest. It's been the case for nearly a decade, or whenever ISE 14.7 (the last version) was released.
For the record, I installed an Ubuntu virtual machine on my Win10 box, and I run ISE 14.7 in that so I can support a few old designs that have Spartan 3ANs.