If I could be reasonably sure that the EU had any chance of reforming itself then I'd vote remain. As it stands now, it is on a stated course of further fiscal parity and defence integration among other federalist aims. Its policy making is now largely around maintaining an army of self-serving politicians and their henchfolk.
Just a few weeks ago the EU had a golden opportunity to show they could change, and attempt a compromise with Cameron, but instead he was sent home with barely crumbs. That short sightedness and arrogance turned out to be a much more dangerous game of poker than they or anyone else expected.
The negativity and politics of fear common in the debate at large I personally find very patronising, rather than concentrating on the issues, and I am sure that too is part of the extraordinary polls we're seeing.
Putting up foreign politicians like Obama, Merkel and today Schäuble is also hardly the way to encourage already disenfranchised floating voters concerned about foreign influence at all levels.
As an earlier poster suggested, the EU needs a bloody nose administering, and needs to fundamentally adjust its course if it is to survive. Regrettably, the only way the EU is capable of changing is to give it a clear message by leaving. For their own survival they'll have to change, and sharpish too, if they are to avoid the wider domino effect predicted.