There have been DMM up on the ISS, and quite a few of them have failed ( that pesky radiation thing, or they needed a calibration) so have had a 300km drop test into a soft landing in the South Pacific ocean. So far none have survived, something about 12 kilometers per second being a little on the high side at the beginning of the fall.
(Hopefully) Obviously I was joking (about the DMM bit).
But on a serous note. With all the (I would expect), electronics up in the ISS. I would have thought they need, quality/reliable/accurate multimeters, up there. So NASA, should/would/have sorted it out, by now.
It could be that the multimeters, just need better protective cases, so they can work in space. If radiation etc, is a problem.
Or put it another way. Say a vital piece of electronics, became faulty, and they had no idea what was wrong. Electronics experts, on the ground, could guide the astronauts, into using the multimeter, to help diagnose what the fault(s), were. There are presumably experiments going on up there, which also might benefit from multimeters.
Since I have never been on the ISS, I have no idea how they fix electrical problems, up there. Maybe they never get their hands dirty. Although I think, I read/heard they fix stuff outside (the space craft), sometimes.
In practice, I presume the main issue, would be the DMM burning up as it hits the atmosphere. It would be interesting to drop samples, of the main/best DMMs, and see which survives the longest, as they burn up. (Joke)