The important point is not some calculation of risk from _this_ increment in the amount of orbital debris.
Rather it's when the orbital debris reaches some critical density, that starts a chain reaction of collisions with intact satellites. A 'collision cascade', with each impact producing a lot more random orbital crap. Ending up with so much that any new space mission passing through the junk zone, has a probability of getting hit that is too high to risk.
No one is able to calculate when that might happen. Just that when it does, space will be closed to humans for generations.
If I was planning a series of missions to set up a colony on Mars, I'd bear in mind the detail that an orbital collision cascade might happen around Earth anytime, making further supply missions (and return of the Mars crews) impossible. This is the kind of scenario Murphy lives for.
Another possibly relevant detail. Who remembers that Nth Korea launched two quite large objects into orbit some time ago? These appeared to be inert, in that they never sent any messages or did any maneuvering. So everyone wonders what they are.
My thought: insurance policies. A ton or so of gravel, with an explosive charge. To fire upon command, or perhaps loss of dead-man signals. Nth Korea saying "if you nuke us, you lose all your military and civilian satellites and access to space, for a long time."