Here some difference which annoys me to dead. My soldering iron is crap, I have the pico. I don't recommend it, if you plan to change the tips frequently.
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Don't know why, but its crappier than the cheapest Chinese clone station. Look at the thread.
On the Pico both are made of plastic.
And the iron stand is also crap, go for the iCon Nano. And i suggest to anyone not to buy the 0102PDLF02 tip. It get to less heat as the station shows you. For example you adjust 350°C on the station an will get about 210°C.
I wouldn't recommend it at all to buy the i-Con Pico or the nano. It has to many things that are bad designed. On/Off switch on the back
. Fixed Power cable, you have to use a sd card to program the station etc... better get a good Hakko 936/937 Ripoff (or Original) and genuine Hakko tips.
Very expensive spare parts like the heating element or soldering iron...