ADC speed can be an issue. The ATmega (and probably also the ATtiny) is really slow, max. 4kS/s or so without overclocking the ADC clock (which will reduce resolution). I believe PIC's are much better in that regard.
An issue I have with parametric search, especially at Mouser, is that often I find that only 20% of the devices I look at have specs beyond type/package/price, so that makes it almost useless. I usually use Digikey to search based on specs, and Mouser if price if my main concern, eg: 'give me the cheapest jellybean part you can find', for example if I need a DAC with at least 8-bit resolution and a 1kS/s sample rate. I also use a Greasemonkey script for Firefox that lets you sort based on price on Digikey (and also filter out results like 'call for price' or 1k minimum order). Digikey is usually much better at normalizing the specs, Mouser might offer you .1A, .10A and 100mA.
Another annoyance is that NXP uses package names different from anybody else, so I have to memorize that SOT-146 is DIP, SOT-163 is SOIC, and so on. Fortunately Mouser does include the standard names.