The reason you get an isolated RS232/USB interface is that the TTL interface on the DB9 isn't isolated.
All the load internal circuitry is referenced to the -ve input. When you stick 500v on the +ve input (of the 500v version) and don't connect the -ve input all internal circuitry is sitting at 500v.
I just tried it, and that is indeed correct. Not good at all...
My Beich has a 1M8 bleed resistor to earth, what does yours measure between the -ve input and earth?
I doubled checked the BK data sheet and manual and don't see any specification for maximum applied voltage on the inputs with respect to earth. I haven't seen that specified on any of the other Chinese clones either.
I checked the isolation on my Beich at 500v and it held up but it has no right to. In one place that isolation is provided by one thickness of pvc insulating tape separating two sheets of aluminium.
Edit: more interesting points.
All these loads are derived somehow from the same basic design, the handbook for my Beich is dated 2006 so the design is quite old.
The processor in yours does look like a 44 pin 8051 and the remains of an SST logo looks likely. My beich has an ATMega. It looks like the processor, display, and remote control protocol are the only areas all the Chinese clones significantly differ.