Isn't this only about Ohms law --- If my motor will draw 10A at 12v I need a wire thickness that will not contribute much to the voltage loss due to wire heating. So 10A at 12vdc dissipates much less at the same resistance (wire thickness) than 10A at 120vdc.
No. The voltage has no effect on the power dissipated by the wire. If your wire carries 12V 10A or 12 kV 10A, it'll still dissipate EXACTLY as much power*. The only thing that matters is the actual wire resistance (i.e. wire gauge).
(*: Assuming it doesn't arc over, at which point all bets are off. Different problem!)
I think you are confusing heat dissipation of the wire versus the total current capacity on the circuit. Power = I * E ; so 12v * 10A is not the same as 12KV * 10A.
ovnr is not confused. You seem to be confusing power dissipated in the wire with power delivered to the load. Power dissipated in the wire is I * E, where I is the current in the wire, and E is the voltage present from one end of the wire to the other end of that individual conducting wire. The voltage across the load does not enter into it. The voltage across the wire is just the current times the resistance of the wire (load resistance doesn't enter into it).
Power delivered to the load is also written as I * E, but this time, the E represents the voltage presented across the load. The equation is still P=I*E, but the letters represent different quantities.
Consider a circuit consisting of two wires carrying power from a source to a load. The heating in a wire depends only on the current running through that wire, not on the voltage as measured from one wire to some different wire. One individual wire "sees" only the current running through it, and the resulting voltage across the wire, as measured from one end of the wire to the other end of that same wire. It doesn't "know" anything about the voltage of the other wire. On the other hand, the power source and the load both see the voltage presented between the two wires.