Hmm, radiation might be more of a concern for modules? SiC or GaN might be better than Si, too, with suitable arrangements to have the driver at a distance, or shielded properly.
SF6 is rather inert stuff IIRC, unless you mean it's particularly nasty from the radiation (radicals), which I can see being a possibility.
At worst, use mil spec hermetically sealed parts (SiC FETs are available in gold-lid TO-220-lookalike packages for about $100 each), or seal up the circuit (with something nice like N2 or Ar) inside a tin.
Tim